CVE-2026-17583

Summary

The affected

Thermo Fisher Applied Biosystems Genetic Analyzers are vulnerable because .fsa/.hid output files can be edited. An attacker could tamper with these files, altering DNA data and resulting in inaccurate DNA test outcomes.

Affected Software

VendorProductVersion RangeStatus
Thermo FisherApplied Biosystems 3500/3500xL Series Data Collection Software0 <= 4.0.2affected
Thermo FisherApplied Biosystems 3730/3730xL Series Data Collection Software0 <= 5.0.2affected
Thermo FisherApplied Biosystems SeqStudio Genetic Analyzer Data Collection Software0 <= 1.2.5affected
Thermo FisherApplied Biosystems SeqStudio Flex Series Instrument Software0 <= 1.2.0affected
Thermo FisherApplied Biosystems GeneMapper ID-X Software0 <= 1.7.3affected
Thermo FisherApplied Biosystems 3130 Series Data Collection Software0 <= 4.1affected
Thermo FisherABI PRISM 3100/3100-Avant Data Collection Software0 <= 2.0affected
Thermo FisherABI PRISM 310 Data Collection Software0 <= 3.1affected

Weaknesses

  • CWE-353: CWE-353

Workarounds

Applied Biosystems 3130 Series Data Collection Software: Product is End of Life (EoL), no update provided ABI PRISM 3100/3100-Avant Data Collection Software: Product is End of Life (EoL), no update provided ABI PRISM 310 Data Collection Software: Product is End of Life (EoL), no update provided

For users who are unable to immediately implement all applicable security updates, Thermo Fisher Scientific recommends implementing the following interim mitigation measures until the applicable updates have been installed: 

  • Maintain a secure chain of custody for files generated by the HID instrumentation throughout the analysis workflow.
  • Store generated files on encrypted, password-protected storage media (for example, encrypted USB drives or encrypted hard drives).
  • Restrict access to generated files to authorized personnel in accordance with your laboratory's access control policies.
  • Apply the principle of least privilege by limiting user permissions on systems operating the HID instrumentation or hosting associated data analysis and secondary analysis software.
  • Leverage firewall rules and network access control lists (NACLs) to restrict internet connectivity to only trusted sources.

For more information, refer to Thermo Fisher's security bulletin. https://documents.thermofisher.com/TFS-Assets/CORP/Product-Guides/fsa_hid_bulletin.pdf

References